According to the daily observation data of meteorological stations in the Hanjiang river ecological economic region from 1964 to 2013,we analyzed the trends,spatial changes,abrupt changes and cycles of dry-wet climate factors through climate inclination rate,Kriging interpolation,M-K mutation test,and wavelet analysis. Results suggest that the study region generally experienced a change from wet to dry. Annual precipitation,potential evapotranspiration,dry-wet index and water deficit all displayed a linear downward trend,with their sudden changes happened in 2005,1972,2006,and 2005,respectively. The dry-wet cycle is 5-year,15-year and 25-year in time scale. Moreover,the study region can be roughly divided into humid and semi-humid regions,and each dry-wet climate factor presents a trend ofsmall in mountainous area and large in plain areain space,which gradually becomes dry along the Hanjiang river from the southeast to the northwest. In conclusion,the dry-wet climate in the Hanjiang river basin is relatively complex and has gradually become dry. We should pay necessary attention to it and take scientific and feasible drought-resisting measures in response to dry-wet climate change.