DOI: 10.1016/j.ecoenv.2019.110101
论文题名: Flumethrin at honey-relevant levels induces physiological stresses to honey bee larvae (Apis mellifera L.) in vitro
作者: Qi S. ; Zhu L. ; Wang D. ; Wang C. ; Chen X. ; Xue X. ; Wu L.
刊名: Ecotoxicology and Environmental Safety
ISSN: 1476513
出版年: 2020
卷: 190 语种: 英语
英文关键词: Bee larvae
; Development disruption
; Flumethrin
; Oxidative stress
Scopus关键词: catalase
; flumethrin
; glutathione
; glutathione reductase
; glutathione transferase
; lipid peroxide
; malonaldehyde
; peroxidase
; superoxide dismutase
; gene expression
; honey
; honeybee
; larva
; oxidative stress
; physiological response
; pyrethroid pesticide
; risk assessment
; adulthood
; Amems gene
; Amhex10869 gene
; animal experiment
; Apis mellifera
; Article
; Basket gene
; colony formation
; controlled study
; Dscam gene
; ecotoxicity
; gene
; gene expression regulation
; honey
; in vitro study
; larva
; larval development
; lipid peroxidation
; metamorphosis
; Mfe gene
; mortality
; nonhuman
; oxidative stress
; pupation
; Vtg gene
; Acari
; Apis mellifera
; Apoidea
; Varroa
英文摘要: Varroa mites often inflict heavy losses on the global bee industry and there are few effective control options. Among these methods to control mites, pesticides are extensively used as a cheap, easy to use, and high-efficiency control measure. However, bees are sensitive to many pesticides; thus, a balance between losses induced by drugs and maximum benefits are important for beekeeping and risk assessment. In this study, the effects of flumethrin, a pyrethroid miticide used on bee colonies, was evaluated using bee larvae reared in vitro. We found that flumethrin induced significant mortality during larval metamorphosis and adult emergence. After continuous exposure during the larval stage, significant changes were observed in antioxidative enzymes (SOD and CAT), lipid peroxidation (MDA, LPO, and POD), and detoxification enzymes (GSH, GST, and GR) in the late instar larvae before pupation. It is also noteworthy that flumethrin significantly regulated the expression of immune (Basket and Dscam) and developmental (Amems, Amhex10869, Vtg and Mfe) genes in larvae, which influences can also be found in the subsequent pupae and adult stages. These findings indicate that flumethrin itself is toxic to bee larvae and has potential risks during colony development. Bees are important pollinators and the sustainable and healthy development of colonies is the foundation of pollinating success for agricultural production. This study would provide some useful thinking for pesticides application techniques and processes in risk assessment of pesticides to bee larvae, even colony. © 2019 Elsevier Inc. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/159142
Appears in Collections: 气候变化与战略
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作者单位: Risk Assessment Laboratory for Bee Products Quality and Safety of the Ministry of Agriculture, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, 100093, China; College of Life Sciences, Peking University, 5 Yiheyuan Road, Beijing, 100871, China; Chinese Research Academy of Environmental Sciences, Beijing, 10012, China; Shenzhen Noposion Agrochemicals Co., Ltd, 113-Tiegang Shuiku Road, Xixiang, Shenzhen, 518102, China
Recommended Citation:
Qi S.,Zhu L.,Wang D.,et al. Flumethrin at honey-relevant levels induces physiological stresses to honey bee larvae (Apis mellifera L.) in vitro[J]. Ecotoxicology and Environmental Safety,2020-01-01,190