DOI: 10.1016/j.scib.2020.10.001
论文题名: Synergistic Ni/Cu catalyzed migratory arylsilylation of terminal olefins
作者: Zhao B. ; Li Y. ; Li H. ; Belal M. ; Zhu L. ; Yin G.
刊名: Science Bulletin
ISSN: 20959273
出版年: 2021
卷: 66, 期: 6 起始页码: 570
结束页码: 577
语种: 英语
中文关键词: Alkene difunctionalization
; Arylsilylation
; Metal migration
; Regioselectivity
; Synergistic catalysis
英文关键词: Carbon
; Catalysis
; Ligands
; Reagents
; Mechanistic studies
; Mild reaction conditions
; Organosilanes
; Side products
; Steric hindrances
; Terminal alkenes
; Terminal olefins
; Transmetalation
; Olefins
英文摘要: Synthesis of organosilanes from alkenes is a very important topic owing to their wide applications. A Ni/Cu dual metal-catalyzed arylsilylation of terminal alkenes, featuring migratory selectivity, has been developed. A wide diversity of aliphatic silanes have been prepared from terminal alkenes, aryl halides and Suginome's reagent. This protocol is highlighted by excellent regioselectivity, mild reaction conditions and good functional group tolerance. In addition to benzylic positions, carbon–carbon bonds can also be constructed at allylic positions. Preliminary mechanistic studies suggest that the copper cocatalyst promotes the transmetalation of Suginome's reagent, and the addition of a PyrOx ligand inhibits the formation of side-products from the carbon-Heck pathway. Moreover, studies toward the nature of the PyrOx ligand revealed that the steric hindrance of the oxazoline moiety greatly affects the chain–walking process, but not the arylation step. © 2020 Science China Press Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/170512
Appears in Collections: 气候变化与战略
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作者单位: The Institute for Advanced Studies, Wuhan University, Wuhan, 430072, China; Institute of Biomedical Materials Industry Technology, Hubei Engineering University, Xiaogan, 432000, China
Recommended Citation:
Zhao B.,Li Y.,Li H.,et al. Synergistic Ni/Cu catalyzed migratory arylsilylation of terminal olefins[J]. Science Bulletin,2021-01-01,66(6)