DOI: 10.1016/j.atmosenv.2013.11.072
Scopus记录号: 2-s2.0-84891113129
论文题名: Health risk assessment for residents exposed to atmospheric diesel exhaust particles in southern region of Taiwan
作者: Chio C ; -P ; , Liao C ; -M ; , Tsai Y ; -I ; , Cheng M ; -T ; , Chou W ; -C
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2014
卷: 85 起始页码: 64
结束页码: 72
语种: 英语
英文关键词: Diesel exhaust particles
; DNA damage
; Particulate matter
; Probabilistic risk assessment
; Tumor incidence
Scopus关键词: Air pollution exposures
; Diesel exhaust particles
; DNA damages
; Environmental and health risks
; Mitigation strategy
; Mitochondrial dysfunction
; Particulate Matter
; Probabilistic Risk Assessment
; Air pollution
; DNA
; Estimation
; Health risks
; Particles (particulate matter)
; Risk assessment
; Tumors
; Diseases
; biological marker
; adaptive management
; atmospheric pollution
; biomarker
; cancer
; data set
; diesel engine
; disease incidence
; dose-response relationship
; exhaust emission
; genotoxicity
; health impact
; health risk
; particulate matter
; pollution exposure
; public health
; resident population
; risk assessment
; temporal analysis
; tumor
; air pollutant
; air pollution
; article
; atmospheric dispersion
; cancer incidence
; cancer risk
; controlled study
; diesel exhaust particle
; DNA damage
; environmental exposure
; exhaust gas
; health hazard
; human
; particulate matter
; precancer
; priority journal
; risk assessment
; Taiwan
; Kaohsiung
; Taiwan
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: Evidence shows a strong association among air pollution, oxidative stress (OS), deoxyribonucleic acid (DNA) damage, and diseases. Recent studies indicated that the aging, human neurodegenerative diseases and cancers resulted from mitochondrial dysfunction and OS. The purpose of this study is to provide a probabilistic risk assessment model to quantify the atmospheric diesel exhaust particles (DEP)-induced pre-cancer biomarker response and cancer incidence risk for residents in south Taiwan. We conducted entirely monthly particulate matter sampling data at five sites in Kaohsiung of south Taiwan in the period 2002-2003. Three findings were found: (i) the DEP dose estimates and cancer risk quantification had heterogeneously spatiotemporal difference in south Taiwan, (ii) the pre-cancer DNA damage biomarker and cancer incidence estimates had a positive yet insignificant association, and (iii) all the estimates of cancer incidence in south Taiwan populations fell within and slight lower than the values from previous cancer epidemiological investigations. In this study, we successfully assessed the tumor incidence for residents posed by DEP exposure in south Taiwan compared with the epidemiological approach. Our approach provides a unique way for assessing human health risk for residences exposed to atmospheric DEP depending on specific combinations of local and regional conditions. Our work implicates the importance of incorporating both environmental and health risk impacts into models of air pollution exposure to guide adaptive mitigation strategies. © 2013 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/80773
Appears in Collections: 气候变化事实与影响
There are no files associated with this item.
作者单位: Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei 100, Taiwan; Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei 106, Taiwan; Department of Environmental Resources Management, Chia Nan University of Pharmacy and Science Tainan 717, Taiwan; Department of Environmental Engineering, National Chung Hsing University, Taichung 402, Taiwan; Department of Biomedical Engineering and Environmental Science, National Tsing Hua University, Hsinchu 300, Taiwan
Recommended Citation:
Chio C,-P,, Liao C,et al. Health risk assessment for residents exposed to atmospheric diesel exhaust particles in southern region of Taiwan[J]. Atmospheric Environment,2014-01-01,85