DOI: 10.1016/j.atmosenv.2015.08.089
Scopus记录号: 2-s2.0-84942013194
论文题名: Day and night variation in chemical composition and toxicological responses of size segregated urban air PM samples in a high air pollution situation
作者: Jalava P ; I ; , Wang Q ; , Kuuspalo K ; , Ruusunen J ; , Hao L ; , Fang D ; , Väisänen O ; , Ruuskanen A ; , Sippula O ; , Happo M ; S ; , Uski O ; , Kasurinen S ; , Torvela T ; , Koponen H ; , Lehtinen K ; E ; J ; , Komppula M ; , Gu C ; , Jokiniemi J ; , Hirvonen M ; -R
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2015
卷: 120 起始页码: 427
结束页码: 437
语种: 英语
英文关键词: Air quality
; Cytotoxicity
; In vitro
; Inflammation
; Particulate matter
; Toxicology
Scopus关键词: Air pollution
; Air quality
; Atmospheric chemistry
; Chemical analysis
; Chemical compounds
; Cytotoxicity
; High resolution transmission electron microscopy
; Meteorological instruments
; Particle size
; Pollution
; Toxicity
; Transmission electron microscopy
; In-vitro
; Inflammation
; Particulate air pollution
; Particulate Matter
; Photochemical activity
; Toxicological analysis
; Toxicological properties
; Toxicology
; Polycyclic aromatic hydrocarbons
; aluminum
; ammonium nitrate
; ammonium sulfate
; arsenic
; barium ion
; cadmium
; calcium ion
; chromium
; copper
; ferric ion
; iron
; lead
; magnesium
; manganese
; metal
; molybdenum
; nickel
; nitrate
; polycyclic aromatic hydrocarbon
; potassium
; rubidium ion
; selenium
; silver
; sodium
; strontium
; sulfate
; titanium
; vanadium
; zinc
; zinc ion
; air mass
; air quality
; air sampling
; atmospheric pollution
; chemical composition
; genotoxicity
; health risk
; industrialization
; PAH
; particle size
; particulate matter
; phytochemistry
; public health
; sampler
; solar radiation
; toxicology
; urban atmosphere
; wind direction
; air pollution
; animal cell
; Article
; cell cycle
; chemical composition
; controlled study
; cytotoxicity
; genotoxicity
; inflammation
; macrophage
; mouse
; nonhuman
; particle size
; particulate matter
; photooxidation
; priority journal
; solar radiation
; toxicology
; transmission electron microscopy
; China
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: Urban air particulate pollution is a known cause for adverse human health effects worldwide. China has encountered air quality problems in recent years due to rapid industrialization. Toxicological effects induced by particulate air pollution vary with particle sizes and season. However, it is not known how distinctively different photochemical activity and different emission sources during the day and the night affect the chemical composition of the PM size ranges and subsequently how it is reflected to the toxicological properties of the PM exposures. The particulate matter (PM) samples were collected in four different size ranges (PM10-2.5; PM2.5-1; PM1-0.2 and PM0.2) with a high volume cascade impactor. The PM samples were extracted with methanol, dried and thereafter used in the chemical and toxicological analyses. RAW264.7 macrophages were exposed to the particulate samples in four different doses for 24 h. Cytotoxicity, inflammatory parameters, cell cycle and genotoxicity were measured after exposure of the cells to particulate samples. Particles were characterized for their chemical composition, including ions, element and PAH compounds, and transmission electron microscopy (TEM) was used to take images of the PM samples. Chemical composition and the induced toxicological responses of the size segregated PM samples showed considerable size dependent differences as well as day to night variation. The PM10-2.5 and the PM0.2 samples had the highest inflammatory potency among the size ranges. Instead, almost all the PM samples were equally cytotoxic and only minor differences were seen in genotoxicity and cell cycle effects. Overall, the PM0.2 samples had the highest toxic potential among the different size ranges in many parameters. PAH compounds in the samples and were generally more abundant during the night than the day, indicating possible photo-oxidation of the PAH compounds due to solar radiation. This was reflected to different toxicity in the PM samples. Some of the day to night difference may have been caused also by differing wind directions transporting air masses from different emission sources during the day and the night. The present findings indicate the important role of the local particle sources and atmospheric processes on the health related toxicological properties of the PM. The varying toxicological responses evoked by the PM samples showed the importance of examining various particle sizes. Especially the detected considerable toxicological activity by PM0.2 size range suggests they're attributable to combustion sources, new particle formation and atmospheric processes. © 2015 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/81515
Appears in Collections: 气候变化事实与影响
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作者单位: University of Eastern Finland, Department of Environmental Science, Kuopio, Finland; Nanjing University, School of the Environment, Nanjing, China; University of Eastern Finland, Department of Applied Physics, Kuopio, Finland; Finnish Meteorological Institute, Kuopio, Finland; VTT Technical Research Center of Finland, Finland; National Institute for Health and Welfare, Kuopio, Finland
Recommended Citation:
Jalava P,I,, Wang Q,et al. Day and night variation in chemical composition and toxicological responses of size segregated urban air PM samples in a high air pollution situation[J]. Atmospheric Environment,2015-01-01,120